Psychiatric Technician Practice Exam

Which medication type is contraindicated with lithium?

1. Antidepressants

2. Diuretics

3. Antipsychotics

4. Stimulants

The correct answer is: Diuretics

Lithium is a medication commonly used to treat bipolar disorder and is known for its narrow therapeutic window, meaning that the right dose is crucial to avoid toxicity. Diuretics are contraindicated with lithium primarily because they can lead to significant fluctuations in sodium levels and renal function. When diuretics are used, they can cause dehydration and a reduced blood volume, leading to increased reabsorption of lithium in the kidneys. This can elevate lithium levels in the blood to potentially toxic levels, resulting in serious side effects. Therefore, the use of diuretics alongside lithium requires careful monitoring and may often be avoided to prevent these complications. In contrast, the other medication types listed—antidepressants, antipsychotics, and stimulants—are not directly contraindicated with lithium. While their interactions may require monitoring, they do not pose the same risk as diuretics do in terms of affecting lithium levels and leading to toxicity. Therefore, the specific contraindication of diuretics with lithium is crucial for patient safety and effective management in individuals taking lithium.