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What antidepressant is sometimes prescribed for panic attacks?

  1. Amitriptyline

  2. Tofranil (imipramine)

  3. Sertraline

  4. Fluoxetine

The correct answer is: Tofranil (imipramine)

Tofanil, known generically as imipramine, is a tricyclic antidepressant that has been found effective in treating panic disorder. Its ability to alleviate the symptoms of panic attacks is attributed to its impact on neurotransmitters in the brain, particularly serotonin and norepinephrine. Imipramine helps to stabilize mood and reduce anxiety, making it beneficial for individuals experiencing panic attacks. In addition to its use in panic disorder, imipramine has also been shown to help with other anxiety-related conditions. This makes it a unique option among antidepressants specifically for those struggling with intense episodes of panic, as it can address both anxiety and depressive symptoms concurrently. The other options listed, while effective as antidepressants, are not primarily identified for the treatment of panic attacks in the same way imipramine is. For instance, sertraline and fluoxetine are selective serotonin reuptake inhibitors (SSRIs) and are more commonly prescribed for anxiety disorders, including panic disorder, but imipramine has a historical precedent in treatment options specifically targeting panic attacks. While these SSRIs are also effective, the tricyclic antidepressants like imipramine have a direct approach to managing panic symptoms effectively, contributing to its suitability for