Psychiatric Technician Practice Exam

What distinguishes Depakote (divalproex sodium) from Depakene (valproic acid)?

1. Depakote is more potent

2. Depakote is enteric-coated while Depakene is not

3. Depakote is cheaper

4. Depakote is liquid while Depakene is solid

The correct answer is: Depakote is enteric-coated while Depakene is not

Depakote (divalproex sodium) is distinguished from Depakene (valproic acid) primarily due to its formulation as an enteric-coated medication. This enteric coating allows Depakote to dissolve in the intestines rather than the stomach, which minimizes gastrointestinal irritation and enhances the tolerability of the medication. This aspect is particularly important for patients who may experience stomach upset from medications. The enteric coating also contributes to more consistent absorption, which can be beneficial in maintaining stable blood levels of the drug. While potency, cost, and physical state (liquid vs. solid) may vary between formulations and preparation methods, these factors do not uniquely distinguish between these two specific products in the same manner that the enteric coating does. The enteric-coated design of Depakote is a key feature that sets it apart from Depakene, influencing both its administration and patient adherence to treatment.