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What is the maximum dosage of Thorazine (chlorpromazine) some clients may be administered for a therapeutic effect?

  1. 400-600mg

  2. 800-1,000mg

  3. 1,100-1,500mg

  4. 100-300mg

The correct answer is: 800-1,000mg

The maximum dosage range of Thorazine (chlorpromazine) that can be administered for a therapeutic effect can vary based on the clinical situation and individual patient response. Typically, the range of 800-1,000 mg is recognized as the upper limit for many patients who require more intensive management of psychotic symptoms, particularly in acute settings or severe cases of schizophrenia or other psychotic disorders. Chlorpromazine is an antipsychotic medication that works primarily by blocking dopamine receptors in the brain, leading to a reduction in symptoms such as hallucinations and delusions. In cases where lower doses are ineffective, healthcare providers may find that increasing the dosage up to the range of 800-1,000 mg can lead to a significant improvement in the patient’s condition while still being within generally accepted safety standards for therapeutic levels. It's important to note that dosages above this range, such as those exceeding 1,000 mg, can increase the risk of side effects and should be approached with caution, monitored closely for any adverse reactions. Therefore, the dosage range of 800-1,000 mg reflects what is often considered the maximum effective dosage provided there are no contraindications or significant side effects observed in the patient.