Which treatment is specifically indicated for opioid addiction?

The treatment specifically indicated for opioid addiction among the options provided is methadone. Methadone is a long-acting opioid agonist used in medication-assisted treatment (MAT) for opioid use disorder. It helps to alleviate withdrawal symptoms and cravings without producing the euphoric high associated with the misuse of opioids. By doing so, methadone assists individuals in stabilizing their lives and reduces the risk of relapse.

Naltrexone, on the other hand, is an opioid antagonist that blocks the effects of opioids. It is usually utilized after a patient has been detoxified from opioids to help prevent relapse, but it is not prescribed during active addiction since it can precipitate withdrawal symptoms. Fluoxetine is an antidepressant used mainly for depressive and anxiety disorders, and buspirone is an anxiolytic used for anxiety management. Neither of these is indicated for treating opioid addiction specifically.